Pycnogenol: Pine Bark Extract
What pycnogenol (pine bark extract) is: Pycnogenol, is a patented combination of 40 or extra plant chemical substances, together with flavonoids and antioxidants. It’s extracted from the bark of Pinus maritima (additionally known as Pinus pinaster), native to southern France. Different pine bark dietary supplements are in the marketplace, many additionally containing varied flavonoids.
Claims, purported advantages: For hundreds of years pine bark extracts have been used medicinally. Pycnogenol has been promoted as a remedy for almost every thing, together with consideration deficit hyperactivity dysfunction (ADHD), menopausal signs, blood vessel issues, diabetes and its issues, jet lag, erectile dysfunction and hypertension.
What the research present: No less than within the check tube and in animal research, Pycnogenol seems to fight irritation and to kill some most cancers cells.
A lot of the human research on Pycnogenol have been finished by the identical workforce of researchers in Italy and Germany. Pycnogenol has been prescribed with some success in Europe to deal with power venous insufficiency, a syndrome that features swelling of the legs, leg ulcers and varicose veins. A number of preliminary research have discovered that the compound could have some potential as a remedy for diabetic retinopathy (harm to blood vessels within the eye). As a remedy for diabetes itself, it could decrease blood sugar ranges—however analysis outcomes are solely preliminary.
One examine discovered that Pycnogenol diminished LDL (“unhealthy”) ldl cholesterol. A examine by a Chinese language and German workforce discovered that it was useful in treating gentle hypertension. A 2009 examine recommended some profit towards jet lag. However, analysis on individuals with consideration deficit dysfunction in adults failed to point out effectiveness.
In 2010, the perfect examine on pine bark extract (carried out at Stanford College, utilizing a product made in Japan) discovered that the extract didn’t scale back blood strain or produce other advantages in individuals at excessive danger for heart problems. In 2012, an eight-week Italian examine discovered that Pycnogenol diminished menopausal signs resembling scorching flashes, in comparison with a placebo.
A 2012 Cochrane assessment of 15 trials on Pycnogenol for the remedy of bronchial asthma, ADHD, power venous insufficiency, diabetes, erectile dysfunction, hypertension and osteoarthritis concluded that the research have been too small, restricted and doubtlessly biased to attract any conclusions concerning the efficacy or security of the complement.
Negative effects: Pycnogenol can have disagreeable unwanted effects (resembling irritability and fatigue) and might work together with plenty of medication.
Backside line: Extra good scientific trials are wanted. It’s not identified how Pycnogenol compares to different pine bark extracts. Correct dosages are unknown, and longterm security unsure. Pycnogenol shouldn’t be given to youngsters